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Products Details
Product Description
– Bromodomain IN-2 is a pan bromodomain (BD) inhibitor with KD values of 250, 420, 130, 430, 67, 240, 970 nM for BRD4(1), CBP, BRPF1B, BRD7, BRD9, BRDT(1), CECR2 respectively. Bromodomain IN-2 shows antiproliferative activity[1].
Web ID
– HY-149806
Shipping
– Room temperature
Molecular Formula
– C16H17ClN2O
References
– [1]Warstat R, et al. A novel pan-selective bromodomain inhibitor for epigenetic drug design. Eur J Med Chem. 2023 Mar 5;249:115139.
CAS Number
– 2445335-77-1
Molecular Weight
– 288.77
SMILES
– O=C1C2=C(C)NC(C3=C(Cl)C=CC(N)=C3)=C2CCCC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Isoform
– BRD4;BRD7;BRD9;BRDT;BRPF1
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
