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Brimonidine (tartrate)
SKU
HY-B0659A-100 mg
Category Reference compound
Tags Adrenergic Receptor, Endocrinology; Cancer, GPCR/G Protein;Neuronal Signaling
$50 – $150
Products Details
Product Description
– Brimonidine tartrate (UK 14304 tartrate) is a full α2-adrenergic receptor (α2-AR) agonist.
Web ID
– HY-B0659A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Molecular Formula
– C15H16BrN5O6
References
– [1]Andorn, A.C., M.A. Carlson, and R.C. Gilkeson, Specific [3H]UK 14,304 binding in human cortex occurs at multiple high affinity states with alpha 2-adrenergic selectivity and differing affinities for GTP. Life Sci, 1988. 43(22): p. 1805-12.|[2]Cambridge, D., UK-14,304, a potent and selective alpha2-agonist for the characterisation of alpha-adrenoceptor subtypes. Eur J Pharmacol, 1981. 72(4): p. 413-5.|[3]Chopin, P., F.C. Colpaert, and M. Marien, Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J Pharmacol Exp Ther, 1999. 288(2): p. 798-804.
CAS Number
– 70359-46-5
Molecular Weight
– 442.22
Compound Purity
– 99.14
SMILES
– O=C(O)[C@H](O)[C@@H](O)C(O)=O.BrC1=C2N=CC=NC2=CC=C1NC3=NCCN3
Clinical Information
– Launched
Research Area
– Endocrinology; Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)|H2O : 25 mg/mL (ultrasonic)
Target
– Adrenergic Receptor
Isoform
– α adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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