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BRD7552
$45 – $960
Products Details
Product Description
– BRD7552, a potent PDX1 transcription factor inducer, upregulates PDX1 expression in both primary human islets and ductal cells, and induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. BRD7552 increases insulin expression. PDX1 is a key transcription factor involved in pancreas development and β cell function[1].
Web ID
– HY-19694
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C33H33N3O15
References
– [1]Yuan Y, et al. A small-molecule inducer of PDX1 expression identified by high-throughput screening [published correction appears in Chem Biol. 2014 Feb 20;21(2):306]. Chem Biol. 2013;20(12):1513-1522.
CAS Number
– 1137359-47-7
Molecular Weight
– 711.63
Compound Purity
– 99.32
SMILES
– OC[C@@H](O1)[C@@H](OC(NC2=CC=C(C(OCC)=O)C=C2)=O)[C@H](OC(NC3=CC=C(OCO4)C4=C3)=O)[C@@H](OC(NC5=CC=C(OCO6)C6=C5)=O)[C@H]1OC
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– DMSO : ≥ 38 mg/mL
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
