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Products Details
Product Description
– BRD4 Inhibitor-26 is a bromodomain protein 4 (BRD4) inhibitor/nitric oxide-donator. BRD4 Inhibitor-26 inhibits BRD4 (BD1) and BRD4 (BD2) with IC50 values of 0.82 μM and 1.94 μM, respectively. BRD4 Inhibitor-26 can be used for the research of ovarian cancer[1].
Web ID
– HY-152209
Shipping
– Room temperature
Molecular Formula
– C29H27N5O6S
References
– [1]Yuehua Zhang, et al. Design, synthesis and anti-ovarian cancer activities of thieno[2,3-d]pyrimidine based chimeric BRD4 inhibitor/nitric oxide-donator. Eur J Med Chem. 2023 Jan 15;246:114970.
Molecular Weight
– 573.62
SMILES
– [O-][N+]1=C(C(C2=CC=CC=C2)=NO1)COC(COC3=C(C=C(C=C3C)C4=NC5=C(C6=C(S5)CN(CC6)C)C(N4)=O)C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
