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Products Details
Product Description
– BRD4 Inhibitor-19 is a BET inhibitor with an IC50 of 55 nM for BRD4-BD1. BRD4 Inhibitor-19 can be used for multiple myeloma research[1].
Web ID
– HY-146739
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C29H25N5O3
References
– [1]Lincheng Fang, et al. Discovery of 3,5-dimethylisoxazole derivatives as novel, potent inhibitors for bromodomain and extraterminal domain (BET) family. Bioorg Med Chem. 2021 Jun 1;39:116133.
CAS Number
– 2757865-63-5
Molecular Weight
– 491.54
SMILES
– CC1=NOC(C)=C1C2=CC=C3C(C(N(C(N3C)=O)CC4=NN=C(O4)C5=CC=CC=C5)C6=CC=CC=C6)=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Isoform
– BD1
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
