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Products Details
Product Description
– BRD4-IN-4 (Compound 1) is a BRD4 inhibitor (IC50=6.83 μM). BRD4-IN-4 selectively inhibits MV4-11 cell line proliferation and arrests cell at G1 phase. BRD4-IN-4 can be used for research of MLL leukemia[1].
Web ID
– HY-153751
Shipping
– Room temperature
Molecular Formula
– C17H18N2O3S
References
– [1]Feng Y, et al. Design, synthesis and biological evaluation of benzo[cd]indol-2(1H)-ones derivatives as BRD4 inhibitors. Eur J Med Chem. 2018 May 25;152:264-273.
CAS Number
– 304685-40-3
Molecular Weight
– 330.40
SMILES
– O=C1C2=CC=CC3=C(S(=O)(N4CCCC4)=O)C=CC(N1CC)=C32
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
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