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Products Details
Product Description
– BRD2889 is an analog of the alkaloid piperlongumine. BRD2889 is a robust modulator of the GSTP1-ISCU axis in pulmonary hypertension (PH)[1]. BRD2889 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-145413
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H25NO6
References
– [1]Negi V, et al. Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension. Sci Adv. 2021;7(43):eabh3794.
CAS Number
– 1415153-39-7
Molecular Weight
– 447.48
SMILES
– COC1=C(C=C(C=C1OC)/C=C/C(N2C(C(C#CC3=CC=C(C=C3)OC)=CCC2)=O)=O)OC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Gutathione S-transferase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
