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Products Details
Product Description
– BRD1991 selectively disrupts Beclin 1/Bcl-2 binding and induces autophagy without triggering apoptosis or other forms of cell death[1].
Web ID
– HY-125191
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C33H35Cl2N3O4
References
– [1]Wei-Chung Chiang, et al. High-Throughput Screens To Identify Autophagy Inducers That Function by Disrupting Beclin 1/Bcl-2 Binding. ACS Chem Biol. 2018 Aug 17;13(8):2247-2260.Â
CAS Number
– 2235468-02-5
Molecular Weight
– 608.55
SMILES
– CN1C2=CC=CC=C2C3=C1C(N(C(CO)C)CC(C)C(CN(C(C4=CC(Cl)=CC(Cl)=C4)=O)C)OCC5=CC=CC=C53)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family;Beclin1
Pathway
– Apoptosis;Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
