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BRD 4354 (ditrifluoroacetate)
$108
Only 1000 item(s) left in stock.
Products Details
Product Description
– BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9, with IC50s of 0.85 and 1.88 μM, respectively[1].
Web ID
– HY-112719B
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H25ClF6N4O5
References
– [1]Boskovic ZV, ET AL. Inhibition of Zinc-Dependent Histone Deacetylases with a Chemically Triggered Electrophile. ACS Chem Biol. 2016 Jul 15;11(7):1844-51.
Molecular Weight
– 610.93
Compound Purity
– 98.52
SMILES
– OC1=C2N=CC=CC2=C(Cl)C=C1C(N3CCN(CC)CC3)C4=CC=CN=C4.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– HDAC
Isoform
– HDAC5;HDAC9
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
