Products Details

Product Description

– BRCA1-IN-1 is a novel small-molecule-like BRCA1 inhibitor with IC50 and Ki of 0.53 μM and 0.71 μM, respecrively.

Web ID

– HY-100863

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C27H33F2N4O6P

References

– [1]Na Z, et al. Discovery of cell-permeable inhibitors that target the BRCT domain of BRCA1 protein by using a small-molecule microarray. Angew Chem Int Ed Engl. 2014 Aug 4;53(32):8421-6.

CAS Number

– 1622262-74-1

Molecular Weight

– 578.54

SMILES

– O=C(N[C@@H](CC(F)(F)P(O)(O)=O)C(NCC(NCCCCC1=CC=CC=C1)=O)=O)CCC2=CNC3=C2C=CC=C3

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– PARP

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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