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Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT
SKU
HY-148820-1 mg
Category Reference compound
Tags Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage, Cancer, Drug-Linker Conjugates for ADC;Topoisomerase
$830 – $3,350
Products Details
Product Description
– Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a agent-linker conjugate that composed of a potent topoisomerase I inhibitor and a linker to make antibody agent conjugate (ADC)[1].
Web ID
– HY-148820
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C36H38BrN5O9
References
– [1]Phillips AC, et, al. Anti-c-met antibody drug conjugates. WO2022232834A1.
CAS Number
– 2857037-70-6
Molecular Weight
– 764.62
Compound Purity
– 98.84
SMILES
– BrCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC12CC(C2)(C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(OCO8)=C8C=C73)C1)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Drug-Linker Conjugates for ADC;Topoisomerase
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
Product type
– Reference compound
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