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BQCA
SKU
HY-101858-10 mg
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, mAChR, Neurological Disease
$50 – $350
Products Details
Product Description
– BQCA a highly selective allosteric modulator of the M1 mAChR.
Web ID
– HY-101858
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C18H15NO4
References
– [1]Ma L, et al. Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15950-5.|[2]Shirey JK, et al. A selective allosteric potentiator of the M1 muscarinic acetylcholine receptorincreases activity of medial prefrontal cortical neurons and restores impairments in reversal learning. J Neurosci. 2009 Nov 11;29(45):14271-86.
CAS Number
– 338747-41-4
Molecular Weight
– 309.32
Compound Purity
– 98.38
SMILES
– O=C(C1=CN(CC2=CC=C(OC)C=C2)C3=C(C=CC=C3)C1=O)O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 4.17 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– mAChR
Isoform
– mAChR1
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.