Download Files:
Bofutrelvir
$280
Only 1000 item(s) left in stock.
Products Details
Product Description
– Bofutrelvir (FB2001) is a SARS-CoV-2 main protease Mpro inhibitor with an IC50 value of 53 nM and an EC50 value of 0.53 μM. Bofutrelvir exhibits potent antiviral efficacy against several current SARS-CoV-2 variants with EC50 values of 0.26-0.42 μM. Bofutrelvir has an additive antiviral effect when combined with Remdesivir (HY-104077)[1][2].
Web ID
– HY-133894
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Applications
– COVID-19-anti-virus
Molecular Formula
– C25H32N4O4
References
– [1]Ullrich S, Nitsche C. The SARS-CoV-2 main protease as drug target. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127377.|[2]Shang W, et al. In vitro and in vivo evaluation of the main protease inhibitor FB2001 against SARS-CoV-2. Antiviral Res. 2022 Dec;208:105450.
CAS Number
– 2103278-86-8
Molecular Weight
– 452.55
Compound Purity
– 96.0
SMILES
– O=C(C(N1)=CC2=C1C=CC=C2)N[C@@H](CC3CCCCC3)C(N[C@H](C=O)C[C@H]4C(NCC4)=O)=O
Clinical Information
– Phase 3
Research Area
– Infection
Solubility
– DMSO : 100 mg/mL (ultrasonic)|DMSO : 250 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
