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Boc-Val-Ala-PAB
$50 – $390
Products Details
Product Description
– Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs)[1][2].
Web ID
– HY-136547
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H31N3O5
References
– [1]HP Wilson, et al. Pyrrolobenzodiazepines and conjugates thereof: World Intellectual Property Organization, WO2016037644. 2016-03-17. |[2]HP Wilson, et al. Preparation of pyrrolobenzodiazepine dimers and their conjugates with cell binding agents, especially pyrrolobenzodiazepine dimer drug linker antibody conjugates and their use for treating proliferative diseases, particularly cancer: World Intellectual Property Organization, WO2016038383. 2016-03-17
CAS Number
– 1884577-99-4
Molecular Weight
– 393.48
Compound Purity
– 98.24
SMILES
– O=C(N[C@@H](C)C(NC(C=C1)=CC=C1CO)=O)[C@H](C(C)C)NC(OC(C)(C)C)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
