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Products Details
Product Description
– Boc-MIF-1-Am (compound 2) is a human dopamine D2 receptor enhancer (EC50=17.82 nM) and is a bioconjugate of melanostatin (MIF-1) and amantadine. Boc-MIF-1-Am (200 μM) exhibited mild neurotoxicity in SH-SY5Y cells[1].
Web ID
– HY-155466
Shipping
– Room temperature
Molecular Formula
– C28H46N4O5
References
– [1]Silva-Reis S C et al. Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D2 Receptors[J]. ACS Medicinal Chemistry Letters, 2023.
Molecular Weight
– 518.69
SMILES
– O=C(N[C@@H](CC(C)C)C(NCC(NC1(C[C@H](C2)C3)C[C@H]3C[C@H]2C1)=O)=O)[C@H]4N(C(OC(C)(C)C)=O)CCC4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
