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BMS-986299
$130 – $1,100
Products Details
Product Description
– BMS-986299 (compound 112) is a first-in-class NLRP3 inflammasome agonist with an EC50 of 1.28 μM. (patent WO2018152396A1).
Web ID
– HY-139396
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H19N7O
References
– [1]Gary Glick, et al. Substituted imidazo-quinolines as nlrp3 modulators. WO2018152396A1.
CAS Number
– 2242952-69-6
Molecular Weight
– 349.39
Compound Purity
– 99.95
SMILES
– O=C(C)N(CC)CC1=NC2=C(N1)C3=C(C=C(C4=NNC=C4)C=C3)N=C2N
Clinical Information
– Phase 1
Research Area
– Cancer; Inflammation/Immunology
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)
Target
– NOD-like Receptor (NLR)
Isoform
– NLRP3
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
