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BMS-986187
$95 – $650
Products Details
Product Description
– BMS-986187 is an δ-opioid receptor-selective positive allosteric modulator (PAM) with an EC50 of 0.03 μM and a pKB of 6.02 (∼1 μM). BMS-986187 has no observable PAM activity at the μ-receptor (EC50=3 μM)[1].
Web ID
– HY-120613
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C31H34O4
References
– [1]Neil T Burford, et al. Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor. J Med Chem. 2015 May 28;58(10):4220-9.
CAS Number
– 684238-37-7
Molecular Weight
– 470.60
Compound Purity
– 98.93
SMILES
– CC1=C(C=CC=C1)COC2=CC=C(C=C2)C3C4=C(OC(CC(C)(C5)C)=C3C5=O)CC(C)(C)CC4=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 25 mg/mL (ultrasonic)
Target
– Opioid Receptor
Isoform
– δ Opioid Receptor/DOR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
