BMS-817399

$315

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Products Details

Product Description

– BMS-817399 is a potent, selective, and orally bioavailable CCR1 antagonist. BMS-817399 exhibits CCR1 binding affinity and chemotaxis inhibition potencies of 1 and 6 nM (IC50), respectively. BMS-817399 can be used for the research of rheumatoid arthritis[1].

Web ID

– HY-15546

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C23H36ClN3O4

References

– [1]Santella JB 3rd, et al. Discovery of the CCR1 antagonist, BMS-817399, for the treatment of rheumatoid arthritis. J Med Chem. 2014;57(18):7550-7564.

CAS Number

– 1202400-18-7

Molecular Weight

– 454.00

SMILES

– O[C@@](CCN1C([C@@H](C(C)C)NC(NCC(C)(O)C)=O)=O)(C(C=C2)=CC=C2Cl)C(C)(C1)C

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– CCR

Isoform

– CCR1

Pathway

– GPCR/G Protein;Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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