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Products Details
Product Description
– BMS-770767 is an 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor in type 2 diabetes. 11β-HSD1 is an important enzyme that is widely expressed in liver, adipose tissue and other tissues and plays an important role in metabolic diseases such as diabetes and obesity[1].
Web ID
– HY-107124
Shipping
– Room temperature
Molecular Formula
– C19H18ClN3O2
References
– [1]Brad D Maxwell, et al. The synthesis and analysis of [phenyl-14 C(U)]BMS-770767 and [13 C6 ]BMS-770767 for use in discovery biotransformation, human ADME and bioanalytical studies. J Labelled Comp Radiopharm. 2016 Dec;59(14):657-664.
CAS Number
– 1875067-34-7
Molecular Weight
– 355.82
SMILES
– OC12CC(CC2)(C3=NN=C4N3C=CC=C4OC5=C(C=CC=C5)Cl)CC1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– 11β-HSD
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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