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BMS-193885 (L-Lactic acid)

SKU HY-107727-Get quote Category Reference compound Tags GPCR/G Protein;Neuronal Signaling, Neurological Disease, Neuropeptide Y Receptor

Products Details

Product Description

– BMS-193885 (L-Lactic acid) is a potent, selective, and brain-penetrant neuropeptide Y1 receptor antagonist. BMS-193885 has a Ki value of 3.3 nM for the neuropeptide Y1 receptor, competitively acts on the neuropeptide Y binding site, and can reduce food intake and body weight through central Y1 inhibition[1].

Web ID

– HY-107727

Shipping

– Room temperature

Molecular Formula

– C36H48N4O9

References

– [1]Ildiko Antal-Zimanyi, et al. Pharmacological characterization and appetite suppressive properties of BMS-193885, a novel and selective neuropeptide Y(1) receptor antagonist. Eur J Pharmacol. 2008 Aug 20;590(1-3):224-32.

CAS Number

– 679839-66-8

Molecular Weight

– 680.79

SMILES

– COC(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC(NC(NCCCN3CCC(C4=CC(OC)=CC=C4)CC3)=O)=CC=C2)=O.OC([C@@H](O)C)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Neuropeptide Y Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.