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BMS-193885 (L-Lactic acid)
SKU
HY-107727-Get quote
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, Neurological Disease, Neuropeptide Y Receptor
Products Details
Product Description
– BMS-193885 (L-Lactic acid) is a potent, selective, and brain-penetrant neuropeptide Y1 receptor antagonist. BMS-193885 has a Ki value of 3.3 nM for the neuropeptide Y1 receptor, competitively acts on the neuropeptide Y binding site, and can reduce food intake and body weight through central Y1 inhibition[1].
Web ID
– HY-107727
Shipping
– Room temperature
Molecular Formula
– C36H48N4O9
References
– [1]Ildiko Antal-Zimanyi, et al. Pharmacological characterization and appetite suppressive properties of BMS-193885, a novel and selective neuropeptide Y(1) receptor antagonist. Eur J Pharmacol. 2008 Aug 20;590(1-3):224-32.
CAS Number
– 679839-66-8
Molecular Weight
– 680.79
SMILES
– COC(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC(NC(NCCCN3CCC(C4=CC(OC)=CC=C4)CC3)=O)=CC=C2)=O.OC([C@@H](O)C)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Neuropeptide Y Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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