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BMS-1001 (hydrochloride)
SKU
HY-120635-10 mg
Category Reference compound
Tags Cancer; Inflammation/Immunology, Immunology/Inflammation, PD-1/PD-L1
$231 – $2,394
Products Details
Product Description
– BMS-1001 hydrochloride is an orally active human PD-L1/PD-1 immune checkpoint inhibitor. BMS-1001 hydrochloride exhibits low-toxicity in cells[1].
Web ID
– HY-120635
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C35H35ClN2O7
References
– [1]Skalniak L, et al. Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells. Oncotarget. 2017 Aug 7;8(42):72167-72181.
CAS Number
– 2113650-04-5
Molecular Weight
– 631.11
Compound Purity
– 99.32
SMILES
– OC[C@@H](NCC1=CC(C)=C(C=C1OCC2=CC=CC(C#N)=C2)OCC3=CC=CC(C4=CC=C5OCCOC5=C4)=C3C)C(O)=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– DMSO : 12.5 mg/mL (ultrasonic)
Target
– PD-1/PD-L1
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.