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Blarcamesine (hydrochloride)
$110 – $1,012
Products Details
Product Description
– Blarcamesine hydrochloride (Anavex 2-73) is a Sigma-1 Receptor agonist with an IC50 of 860 nM.
Web ID
– HY-101864
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C19H24ClNO
References
– [1]Villard V, et al. Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma 1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative. J Psychopharmacol. 2011 Aug;25(8):1101-17.|[2]Valentine Lahmy, et al. Blockade of Tau Hyperphosphorylation and Aβ1-42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic andσ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer’s Disease. Neuropsychopharmacology. 2013 Aug; 38(9): 1706-1723.
CAS Number
– 195615-84-0
Molecular Weight
– 317.85
Compound Purity
– 99.87
SMILES
– CN(C)CC1CCOC1(C2=CC=CC=C2)C3=CC=CC=C3.[H]Cl
Clinical Information
– Phase 2
Research Area
– Neurological Disease; Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– Sigma Receptor
Isoform
– Sigma 1 Receptor
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
