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Products Details
Product Description
– BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 µM. BK50164 binds to CD99 with a KD value of 1.5 µM. BK50164 shows antiproliferative activity. BK50164 induced Apoptosis and cell cycle arrest at Sub-G1 phase[1].
Web ID
– HY-150048
Shipping
– Room temperature
Molecular Formula
– C13H13ClFN5O7
References
– [1]Roland Joseph Billedeau, et al. Ectonucleotidase inhibitors and methods of use thereof. WO2018119284A1.|[2]Balaraman K, et al. Design, synthesis and biological evaluation of Nucleosidic CD99 inhibitors that selectively reduce Ewing sarcoma viability. Eur J Med Chem. 2023 May 5;251:115244.
CAS Number
– 2204291-78-9
Molecular Weight
– 405.72
SMILES
– NC1=NC(Cl)=NC2=C1N=CN2[C@@H]3O[C@H](COC(C(O)=O)C(O)=O)[C@@H](O)[C@@H]3F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;CD73
Pathway
– Apoptosis;Immunology/Inflammation
Product type
– Reference compound
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