Download Files:
Bis-T-23
$571
Only 1000 item(s) left in stock.
Products Details
Product Description
– Bis-T-23 (AG1717), tyrphostin derivative, is an HIV-I integrase inhibitor. Bis-T-23 can promote actin-dependent dynamin oligomerization. Bis-T-23 can be used for the research of HIV and chronic kidney diseases (CKD)[1][2].
Web ID
– HY-123572
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C23H20N4O8
References
– [1]Schiffer M, et al. Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nat Med. 2015;21(6):601-609.|[2]Mazumder, A.,et al. Effects of Tyrphostins, Protein Kinase Inhibitors, on Human Immunodeficiency Virus Type 1 Integrase. Biochemistry, 1995, 34(46), 15111–15122.
CAS Number
– 171674-76-3
Molecular Weight
– 480.43
SMILES
– O=C(/C(C#N)=C/C1=CC(O)=C(C(O)=C1)O)NCCCNC(/C(C#N)=C/C2=CC(O)=C(C(O)=C2)O)=O
Clinical Information
– No Development Reported
Research Area
– Infection; Metabolic Disease; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Dynamin;HIV Integrase
Pathway
– Cytoskeleton;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
