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Bis-propargyl-PEG9
Products Details
Product Description
– Bis-propargyl-PEG9 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG9 can be used to synthesize the bivalent estrogen receptor ligands[1]. Bis-propargyl-PEG9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-133189
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C24H42O10
References
– [1]Shan M, et al. Conformational analysis of bivalent estrogen receptor ligands: from intramolecular to intermolecular binding. Chembiochem. 2011 Nov 25;12(17):2587-98.
CAS Number
– 1351373-47-1
Molecular Weight
– 490.58
SMILES
– C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– PROTAC Linkers
Isoform
– PEG Linkers
Pathway
– PROTAC
Product type
– Reference compound
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