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Products Details
Product Description
– Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Web ID
– HY-141091
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C69H96N12O17S
References
– [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
CAS Number
– 2353409-56-8
Molecular Weight
– 1397.64
SMILES
– [O-]C(C(C=C(C(NCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCC(NCCCN/C(CCOCCOCCOCCOCCNC(CCCC[C@H]1[C@](NC2=O)([H])[C@](N2)([H])CS1)=O)=C(C3=O)C(CC(C)(C)C3)=O)=O)=O)=O)C=C4)=C4C5=C(C=CC(N)=C6)C6=[O+]C7=C5C=CC(N(C)C)=C7)=O
Clinical Information
– No Development Reported
Research Area
– others
Solubility
– 10 mM in DMSO
Target
– Fluorescent Dye
Isoform
– Cleavable Linker
Pathway
– Others
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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