Download Files:
Products Details
Product Description
– BIO7662 is a specific α4β1 antagonist. BIO7662 can be used to study α4β1 integrin-ligand interactions[1][2].
Web ID
– HY-123802
Shipping
– Room temperature
Molecular Formula
– C38H48N6O8S
References
– [1]Chen LL,et al. Evidence that ligand and metal ion binding to integrin alpha 4beta 1 are regulated through a coupled equilibrium. J Biol Chem. 2001 Sep 28;276(39):36520-9.|[2]Egger LA, et al. A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence. J Pharmacol Exp Ther. 2003 Sep;306(3):903-13.
CAS Number
– 327613-10-5
Molecular Weight
– 748.89
SMILES
– O=C(O)[C@@H](NC([C@H]1N(S(=O)(C2=CC=CC=C2)=O)CCC1)=O)CCNC([C@@H](N(C)C(CC3=CC=C(NC(NC4=CC=CC=C4C)=O)C=C3)=O)CC(C)C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Integrin
Pathway
– Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
