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Products Details
Product Description
– BIBU1361 induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6[1].
Web ID
– HY-103438
Shipping
– Room temperature
Molecular Formula
– C22H27ClFN7
References
– [1]Ruchi Ghildiyal, et, al. EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells. Mol Carcinog. 2013, 52,12.
CAS Number
– 793726-84-8
Molecular Weight
– 443.95
SMILES
– CCN(CC1CCN(C2=NC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=N2)CC1)CC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Akt;Apoptosis;mTOR
Pathway
– Apoptosis;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
