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BI 689648
$300 – $2,350
Products Details
Product Description
– BI 689648 is a novel, highly selective aldosterone synthase inhibitor which can inhibit CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively.
Web ID
– HY-101217
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C16H18N4O2
References
– [1]Weldon SM, et al. Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates. J Pharmacol Exp Ther. 2016 Oct;359(1):142-50.
CAS Number
– 1633009-87-6
Molecular Weight
– 298.34
Compound Purity
– 99.20
SMILES
– O=C(N1CCCC2=C1N=CC(C3=CC(COC)=CN=C3)=C2)N
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– DMSO : 30 mg/mL (ultrasonic;warming)
Target
– Cytochrome P450
Isoform
– CYP11
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
