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BI-1408
$571
Only 1000 item(s) left in stock.
Products Details
Product Description
– BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42[1].
Web ID
– HY-112282
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C22H23FN6
References
– [1]Gerlach K, et al. Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators. Bioorg Med Chem. 2018 Jul 23;26(12):3227-3241.
CAS Number
– 2231075-94-6
Molecular Weight
– 390.46
SMILES
– CC1=CC(F)=CC=C1C2=CC=CN3C2=NC(N[C@@H]4CCC(N(CC)N=C5)=C5C4)=N3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– γ-secretase
Pathway
– Neuronal Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
