Download Files:
Products Details
Product Description
– BI-0282 (Compound 1) is a potent MDM2-p53 interaction inhibitor[1].
Web ID
– HY-150620
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C30H23Cl2FN4O4
References
– [1]Ramharter J, et al. Synthesis of MDM2-p53 Inhibitor BI-0282 via a Dipolar Cycloaddition and Late-Stage Davis–Beirut Reaction. Organic Process Research & Development, 2022.
CAS Number
– 1883383-48-9
Molecular Weight
– 593.43
SMILES
– FC1=C(C=CC=C1[C@@H]([C@@H]2N3C4=C5C=CC(C(O)=O)=CC5=N3)[C@]6(C(NC7=C6C=CC(Cl)=C7)=O)N([C@H]2CO4)CC8CC8)Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MDM-2/p53
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
