BGC20-761

$346$554

Products Details

Product Description

– BGC20-761 is a selecvtive 5-HT6 and dopamine receptor antagonist (human receptor Ki values: 5-HT6 (20 nM), 5-HT2A (69 nM), D2 (140 nM). BGC20-761, can enhance long-term memory. BGC20-761 has potential utility as an antipsychotic agent[1].

Web ID

– HY-21995

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C19H22N2O

References

– [1]Ellen S Mitchell, et al. BGC20-761, a novel tryptamine analog, enhances memory consolidation and reverses scopolamine-induced memory deficit in social and visuospatial memory tasks through a 5-HT6 receptor-mediated mechanism. Neuropharmacology. 2006 Mar;50(4):412-20.

CAS Number

– 17375-63-2

Molecular Weight

– 294.39

SMILES

– CN(C)CCC1=C(C2=CC=CC=C2)NC3=C1C=C(OC)C=C3

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– 5-HT Receptor;Dopamine Receptor

Isoform

– 5-HT2 Receptor;5-HT6 Receptor;D2 Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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