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BF 227
$400 – $3,500
Products Details
Product Description
– BF 227 is a candidate for an amyloid imaging probe for PET, with a Ki of 4.3 nM for Aβ1-42 fibrils.
Web ID
– HY-105252A
Storage Temperature
– 4°C (Powder, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C16H16FN3O2S
References
– [1]Kudo Y, et al. Development of amyloid imaging PET probes for an early diagnosis of Alzheimer’s disease. Minim Invasive Ther Allied Technol. 2006;15(4):209-13.|[2]Furukawa K, et al. Amyloid PET in mild cognitive impairment and Alzheimer’s disease with BF-227: comparison to FDG-PET. J Neurol. 2010 May;257(5):721-7.
CAS Number
– 845647-80-5
Molecular Weight
– 333.38
Compound Purity
– 98.88
SMILES
– CN(C)C1=NC=C(S1)/C=C/C2=NC3=CC=C(OCCF)C=C3O2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)
Target
– Amyloid-β
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
