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Bezuclastinib
$590 – $4,900
Products Details
Product Description
– Bezuclastinib (CGT9486; PLX 9486) is a potent inhibitor of c-kit and c-kit D816V (0.0001<IC50<1 μM; extracted from patent WO2014100620 A2, compound P-2007). Bezuclastinib is a tyrosine kinase inhibitor[1][2].
Web ID
– HY-145557
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H17N5O
References
– [1]Guoxian Wu, et al. Preparation of phenylpyrrolopyridinylheteroarylcarboxamide derivatives and analogs for use as c-kit protein kinases or mutant c-kit protein kinases modulators. Patent WO2014100620 A2.|[2]WHO Drug Information, Vol. 35, No. 4, 2021. Geneva: World Health Organization; 2022.
CAS Number
– 1616385-51-3
Molecular Weight
– 331.37
Compound Purity
– 98.59
SMILES
– O=C(C1=NNC(C)=C1C)NC2=CN=C3NC(C4=CC=CC=C4)=CC3=C2
Clinical Information
– Phase 3
Research Area
– Cancer
Solubility
– DMSO : 80 mg/mL (ultrasonic)
Target
– c-Kit
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
