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Betazole

$103$480

Products Details

Product Description

– Betazole (Ametazole), a pyrazole analogue of histamine, is an orally active histamine H2 receptor agonist. Betazole induces gastric acid secretion and causes an immediate and significant increase in common bile duct pressure. Betazole is used as a diagnostic agent known as histalog for investigating gastric acid secretory capacity[1][2][3].

Web ID

– HY-B1557

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C5H9N3

References

– [1]Maples MD, Effects of betazole hydrochloride and cimetidine on common bile pressure and duodenal myoelectric activity in the dog. Am Surg. 1981;47(12):519-521.|[2]Spitz IM, Betazole-induced GIP secretion is not mediated by gastric HCl. Metabolism. 1982;31(4):380-382.|[3]CLAYMAN CB,. A simple oral gastric secretory stimulant (betazole hydrochloride). JAMA. 1961;175:908-909.

CAS Number

– 105-20-4

Molecular Weight

– 111.15

Compound Purity

– 95.08

SMILES

– NCCC1=NNC=C1

Clinical Information

– Launched

Research Area

– Metabolic Disease

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– Histamine Receptor

Isoform

– H2 Receptor

Pathway

– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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