Download Files:
Products Details
Product Description
– BET-IN-2 is a BET inhibitor with an IC50 of 52 nM for BRD4-BD1.
Web ID
– HY-102044
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H29N3O
References
– [1]Hu J, et al. Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor. Eur J Med Chem. 2017 Sep 8;137:176-195.
CAS Number
– 2104688-91-5
Molecular Weight
– 363.50
SMILES
– CC1=C([C@H](C)NC2=CC(N(C3CC3)[C@H](C)C(N4C)=O)=C4C=C2)C=CC(C)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Isoform
– BRD4
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
