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Products Details
Product Description
– BET-IN-17 (compound 16) is a pan-inhibitor of BET with pIC50s of 7.8 and 7.6 for BET BD1 and BET BD2, respectively[1].
Web ID
– HY-155809
Shipping
– Room temperature
Molecular Formula
– C30H36N4O2
References
– [1]Bamborough P, et al. Design and Characterization of 1, 3-Dihydro-2 H-benzo [d] azepin-2-ones as Rule-of-5 Compliant Bivalent BET Inhibitors[J]. ACS Medicinal Chemistry Letters, 2023.. . .
Molecular Weight
– 484.63
SMILES
– CN1C=CC2=C([C@H](C1=O)C)C=CC(CN3CCN(CC3)CC4=CC=C5[C@H](C(N(C=CC5=C4)C)=O)C)=C2
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
