Download Files:
Products Details
Product Description
– BET-IN-12 is an orally avtive inhibitor of bromodomain and extra-terminal (BET) with an IC50 of 0.9 nM for BRD4[1].
Web ID
– HY-150516S
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C30H29D3FN5O2
References
– [1]Hill, Matthew D., et al. Development of BET Inhibitors as Potential Treatments for Cancer: Optimization of Pharmacokinetic Properties. ACS Med Chem Lett. 2022.
CAS Number
– 1800343-11-6
Molecular Weight
– 516.62
SMILES
– CC(C)(O)C(C(F)=C1)=CC(N2[C@@H](C3CCOCC3)C4=CC=CC=C4)=C1C(N=C5)=C2C=C5C(N(N=N6)C)=C6C([2H])([2H])[2H]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
