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Products Details
Product Description
– Besifovir Dipivoxil maleate (LB80380 maleate) is an oral proagent of LB80317. Besifovir Dipivoxil maleate (LB80380 maleate) is effective in hepatitis B virus (HBV) DNA suppression for both treatment-naive and lamivudine-resistant chronic hepatitis B (CHB) patients in preliminary studies[1][2]</sup.
Web ID
– HY-19447A
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C26H38N5O12P
References
– [1]Yuen MF, et al. A randomized placebo-controlled, dose-finding study of oral LB80380 in HBeAg-positive patients with chronic hepatitis B. Antivir Ther. 2006;11(8):977-83.|[2]Lai CL, et al. Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B. Gut. 2014 Jun;63(6):996-1004.
CAS Number
– 441785-26-8
Molecular Weight
– 643.58
SMILES
– NC1=NC=C2N=CN(CC3(OCP(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)CC3)C2=N1.O=C(O)/C=CC(O)=O
Clinical Information
– Phase 4
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HBV
Pathway
– Anti-infection
Product type
– Reference compound
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