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Products Details
Product Description
– Benzoquinonium dibromide is a nicotinic acetylcholine receptors (nAChRs) antagonist, with an IC50 of 0.46 μM. Benzoquinonium dibromide can block neuromuscular and ganglionic transmission[1][2][3].
Web ID
– HY-B1552B
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C34H50Br2N4O2
References
– [1]Walker RJ, et, al. Physiological and pharmacological studies on annelid and nematode body wall muscle. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1993 Sep;106(1):49-58.|[2]BOWMAN WC. The neuromuscular blocking action of benzoquinonium chloride in the cat and in the hen. Br J Pharmacol Chemother. 1958 Dec;13(4):521-30.|[3]Bowman WC, et, al. Neuromuscular blocking and ganglion blocking activities of some acetylcholine antagonists in the cat. J Pharm Pharmacol. 1972 Oct;24(10):762-72.
Molecular Weight
– 706.59
SMILES
– O=C(C(NCCC[N+](CC)(CC)CC1=CC=CC=C1)=C2)C=C(NCCC[N+](CC)(CC)CC3=CC=CC=C3)C2=O.[Br-].[Br-]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
