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Benzamide
$55 – $61
Products Details
Product Description
– Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].
Web ID
– HY-Z0283
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C7H7NO
References
– [1]Cosi C, et al. Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse. Brain Res. 1996 Oct 7;735(2):343-8.
CAS Number
– 55-21-0
Molecular Weight
– 121.14
Compound Purity
– 99.85
SMILES
– NC(C1=CC=CC=C1)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 120 mg/mL (ultrasonic)
Target
– Endogenous Metabolite, PARP
Isoform
– Human Endogenous Metabolite
Pathway
– Cell Cycle/DNA Damage, Epigenetics, Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
