Benzamide

$55$61

Products Details

Product Description

– Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].

Web ID

– HY-Z0283

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C7H7NO

References

– [1]Cosi C, et al. Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse. Brain Res. 1996 Oct 7;735(2):343-8.

CAS Number

– 55-21-0

Molecular Weight

– 121.14

Compound Purity

– 99.85

SMILES

– NC(C1=CC=CC=C1)=O

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : 120 mg/mL (ultrasonic)

Target

– Endogenous Metabolite, PARP

Isoform

– Human Endogenous Metabolite

Pathway

– Cell Cycle/DNA Damage, Epigenetics, Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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