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Benfluorex (hydrochloride)
SKU
HY-B1058-10mM/1mL
Category Reference compound
Tags Metabolic Disease; Cardiovascular Disease, Others
$50 – $55
Products Details
Product Description
– Benfluorex hydrochloride (JP-992 hydrochloride) is a hepatic nuclear factor 4 alpha (HNF4α) activator.
Web ID
– HY-B1058
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H21ClF3NO2
Citations
– Virol J. 2021 Sep 28;18(1):196.|Biochem Pharmacol. 6 August 2022, 115198.|EBioMedicine. 2022 Jul 28;82:104181.|Research Square Print. December 19th, 2022.
References
– [1]Lee SH, et al. Identification of alverine and benfluorex as HNF4α activators. ACS Chem Biol. 2013 Aug 16;8(8):1730-6.|[2]Kohl C, et al. Effects of benfluorex on fatty acid and glucose metabolism in isolated rat hepatocytes: from metabolic fluxes to gene expression. Diabetes. 2002 Aug;51(8):2363-8.
CAS Number
– 23642-66-2
Molecular Weight
– 387.82
Compound Purity
– 99.96
SMILES
– FC(C1=CC(CC(NCCOC(C2=CC=CC=C2)=O)C)=CC=C1)(F)F.[H]Cl
Clinical Information
– Launched
Research Area
– Metabolic Disease; Cardiovascular Disease
Solubility
– DMSO : ≥ 100 mg/mL|H2O : 2.27 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.