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Products Details
Product Description
– Benfluorex (JP-992) is a hepatic nuclear factor 4 alpha (HNF4α) activator.
Web ID
– HY-B1058A
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C19H20F3NO2
Citations
– Biochem Pharmacol. 6 August 2022, 115198.|EBioMedicine. 2022 Jul 28;82:104181.|Research Square Print. December 19th, 2022.|Virol J. 2021 Sep 28;18(1):196.
References
– [1]Lee SH, et al. Identification of alverine and benfluorex as HNF4α activators. ACS Chem Biol. 2013 Aug 16;8(8):1730-6.|[2]Kohl C, et al. Effects of benfluorex on fatty acid and glucose metabolism in isolated rat hepatocytes: from metabolic fluxes to gene expression. Diabetes. 2002 Aug;51(8):2363-8.
CAS Number
– 23602-78-0
Molecular Weight
– 351.36
SMILES
– FC(C1=CC(CC(NCCOC(C2=CC=CC=C2)=O)C)=CC=C1)(F)F
Clinical Information
– Launched
Research Area
– Metabolic Disease; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
