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Belvarafenib (TFA)
$180 – $198
Products Details
Product Description
– Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively[1].
Web ID
– HY-109080A
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H17ClF4N6O3S
References
– [1]WO 2013/100632 A1.
CAS Number
– 2443966-84-3
Molecular Weight
– 592.95
Compound Purity
– 99.0
SMILES
– O=C(C(C1=NC=N2)=CSC1=C2N)NC(C3=C4C(NC(C=CC=C5Cl)=C5F)=NC=C3)=C(C=C4)C.OC(C(F)(F)F)=O
Clinical Information
– Phase 2
Research Area
– Cancer
Solubility
– 10 mM in H2O
Target
– Raf
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
