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Befloxatone

Products Details

Product Description

– Befloxatone (MD-370503) is an orally active, selective and reversible inhibitor of Monoamine Oxidase A (MAO-A) (IC50=4 nM). Befloxatone increases the tissue level of monoamine, striatal dopamine and cortical norepinephrine. Befloxatone has antidepressant potential[1].

Web ID

– HY-120017

Shipping

– Room temperature

Molecular Formula

– C15H18F3NO5

References

– [1]Curet O, et al. Preclinical profile of befloxatone, a new reversible MAO-A inhibitor. J Affect Disord. 1998 Dec;51(3):287-303.

CAS Number

– 134564-82-2

Molecular Weight

– 349.30

SMILES

– O=C1O[C@@H](COC)CN1C2=CC=C(OCC[C@@H](O)C(F)(F)F)C=C2

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Monoamine Oxidase

Isoform

– MAO-A;MAO-B

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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