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Befloxatone
SKU
HY-120017-Get quote
Category Reference compound
Tags Monoamine Oxidase, Neurological Disease, Neuronal Signaling
Products Details
Product Description
– Befloxatone (MD-370503) is an orally active, selective and reversible inhibitor of Monoamine Oxidase A (MAO-A) (IC50=4 nM). Befloxatone increases the tissue level of monoamine, striatal dopamine and cortical norepinephrine. Befloxatone has antidepressant potential[1].
Web ID
– HY-120017
Shipping
– Room temperature
Molecular Formula
– C15H18F3NO5
References
– [1]Curet O, et al. Preclinical profile of befloxatone, a new reversible MAO-A inhibitor. J Affect Disord. 1998 Dec;51(3):287-303.
CAS Number
– 134564-82-2
Molecular Weight
– 349.30
SMILES
– O=C1O[C@@H](COC)CN1C2=CC=C(OCC[C@@H](O)C(F)(F)F)C=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Monoamine Oxidase
Isoform
– MAO-A;MAO-B
Pathway
– Neuronal Signaling
Product type
– Reference compound
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