Beclometasone dipropionate

$60$66

Products Details

Product Description

– Beclometasone dipropionate, the proagent of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate can be used for asthma [1][2].

Web ID

– HY-13571A

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C28H37ClO7

References

– [1]Hrvacić B, et, al. Applicability of an ultrasonic nebulization system for the airways delivery of beclomethasone dipropionate in a murine model of asthma. Pharm Res. 2006 Aug;23(8):1765-75. |[2]Montalbano AM, et, al. Beclomethasone dipropionate and formoterol reduce oxidative/nitrosative stress generated by cigarette smoke extracts and IL-17A in human bronchial epithelial cells. Eur J Pharmacol. 2013 Oct 15;718(1-3):418-27.

CAS Number

– 5534-09-8

Molecular Weight

– 521.04

Compound Purity

– 99.89

SMILES

– C[C@@]12[C@](C[C@H](C)[C@]2(OC(CC)=O)C(COC(CC)=O)=O)([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C1)=O

Clinical Information

– Launched

Research Area

– Inflammation/Immunology; Endocrinology

Solubility

– DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL (ultrasonic)

Target

– Glucocorticoid Receptor;NO Synthase;Reactive Oxygen Species

Isoform

– iNOS

Pathway

– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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