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BCR-ABL-IN-7
SKU
HY-153008-Get quote
Category Reference compound
Tags Bcr-Abl, Cancer, Protein Tyrosine Kinase/RTK
Products Details
Product Description
– BCR-ABL-IN-7 (compound 4) is a WT and T315I mutant ABL kinases inhibitor. BCR-ABL-IN-7 effectively inhibits activities of WT and T315I mutant ABL kinases. BCR-ABL-IN-7 can be used for the research of chronic myeloid leukemia (CML) research[1].
Web ID
– HY-153008
Shipping
– Room temperature
Molecular Formula
– C19H16FN3O3S
References
– [1]Cao R, et al. Discovery of 2-Acylaminothiophene-3-Carboxamides as Multitarget Inhibitors for BCR-ABL Kinase and Microtubules. J Chem Inf Model. 2015 Nov 23;55(11):2435-42.
CAS Number
– 688050-42-2
Molecular Weight
– 385.41
SMILES
– O=C(C1=C(NC(C2=NOC(C3=CC=C(F)C=C3)=C2)=O)SC4=C1CCCC4)N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcr-Abl
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.