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Products Details
Product Description
– BCR-ABL-IN-4 is a BCR-ABL inhibitor with anticancer effects. BCR-ABL-IN-4 inhibits the cancer cell growth with IC50 values of 0.67 nM and 16 nM for K562 cells and BCR-ABL T315I transfected Ba/F3 cells, respectively (WO2021143927A1; compound 11)[1].
Web ID
– HY-142922
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C27H24ClF2N5O4
References
– [1]Yinsheng Zhang, et al. Compound acting as bcr-abl inhibitor. WO2021143927A1.
CAS Number
– 2669790-59-2
Molecular Weight
– 555.96
SMILES
– ClC(F)(F)OC(C=C1)=CC=C1NC(C2=CC(C3=CN=C(CN(C4CC4)C5=O)C5=C3)=C(N6C[C@@H](CC6)O)N=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcr-Abl
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
