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Products Details
Product Description
– Bcl-2-IN-15 (Compound 13d)) is a Bcl-2 inhibitor (IC50: 363 nM). Bcl-2-IN-15 inhibits the proliferation ofNCI leukemia cancer cell line[1].
Web ID
– HY-149625
Shipping
– Room temperature
Molecular Formula
– C37H28F3N5O5S
References
– [1]Ismail HS, et al. Design, molecular modelling and synthesis of novel benzothiazole derivatives as BCL-2 inhibitors. Sci Rep. 2023 Sep 20;13(1):15554.
Molecular Weight
– 711.71
SMILES
– O=C(C1=CC(SC(NC(C2=CC=C(NCCC3=CC=CC=C3)C([N+]([O-])=O)=C2)=O)=N4)=C4C=C1)NC5=CC=C(C=C5)OCC6=CC=C(C(F)(F)F)C=C6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
